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VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma

Science Magazine - Jul 19, 2018
Many clear cell renal cell carcinomas (ccRCCs) have alterations to the gene encoding the von Hippel-Lindau protein (VHL). VHL is a ubiquitin ligase that degrades target proteins when they are prolyl-hydroxylated. Zhang et al. performed a genome-wide ...

A Call for Better Screening for Hereditary Renal Cell Carcinoma

Cancer Network - Jul 11, 2018
It may be time to adopt a broader approach to tumor and matched normal sequencing in patients with advanced renal cell carcinoma (RCC), according to a large new study. In an article published in JAMA, researchers report that germline mutations in ...

Newly Diagnosed Metastatic Renal Cell Carcinoma

OncLive - Jul 11, 2018
Daniel George, MD: Hello, and thank you for joining this OncLive® Peer Exchange® titled “Evolving Treatment Paradigms for Renal Cell Carcinoma.” The standard of care for patients with metastatic renal cell carcinoma continues to change rapidly as novel ...

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Renal cell carcinoma - causes, symptoms, diagnosis, treatment, pathology

What is Renal Cell Carcinoma? It form from epithelial cells in the proximal convoluted tubule of the kidney. Find more videos at http://osms.it/more. Study better ...

Renal Cell Carcinoma for USMLE

Renal Cell Carcinoma Anatomy, Epidemiology, Etiology, Clinical Signs and Symptoms, Treatment and Management. Handwritten, full lecture for medical ...

Renal Cell Carcinoma

Visit: http://www.uctv.tv/) In the United States, there are over 60000 new diagnoses and nearly 14000 deaths from kidney cancer each year. Dr. Won Kim reviews ...

Histopathology Kidney--Renal cell carcinoma

Histopathology Kidney--Renal cell carcinoma.